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synapsyl_reviews_144x277Synapsyl was launched in 2014 and it is marketed as ‘viagra for the brain’, as scientists supposedly call it. Its manufacturers claim it is a 100 percent natural nootropic supplement whose compounds contribute to the health of brain neurotransmitters and who thus boost energy levels, sky-rocket concentration and creative thinking, prevent cognitive decline and enhance memory. The name Synapsyl suggests its impact on the brain. It is related to synapses, which are the links between neurons.

Brain boosters are increasingly popular with healthy people who want to unlock their cognitive potential. These nootropics give them a competitive edge in a highly fast-paced and competitive environment by enhancing memory, concentration and alertness. A little help is even more needed since, as we age, our brain undergoes certain changes that affect its cognitive performance. The most affected brain function is memory: in time, it becomes even harder and harder to recall faces, numbers, and events. After 40, our brain decreases in volume at a 5 percent rate every 10 years. The brain’s chemical balance also changes in time. Starting with early adulthood, dopamine levels drop at a rate of around 10 percent over the course of 10 years and this, together with an increased production of free radicals, leads to gradual cognitive decline.


There are a number of benefits that the product claims can be felt within 30 minutes and will help you unleash your mind‘s potential:

  • Focus: your productivity will increase significantly by being able to multi-task and pay attention to the individual tasks at hand. Your mind will no longer wander aimlessly, but will be able to break down complex concepts.
  • Speed: your response time will be faster. You will be a more rapid learner and you will process information with ease. You will get more done in less time.
  • Protection: its ingredients will protect your brain from cognitive decline and damage brought on with the passing of time. The product will protect your brain from a cognitive decline from oxidative stress when your brain is imbalanced and cannot adequately
  • Memory: learning new things will seem so much easier, you won’t have to dig into your past to remember faces, places or facts. Both your short-term and long-term memory can benefit from Synapsyl.
  • Blood flow: enhanced blood circulation will bring more oxygen and nutrients to the brain and improve its general performance.
  • Energy: your energy levels will skyrocket. You will be able to take on more activities and not crash mid-day or at the end of the day.
  • Mood: one of its ingredients, John’s wort, is known for alleviating depression symptoms and thus boosting your mood. Also, when we are more productive and energetic, we tend to have more self-confidence and be in an overall better mood. Ginkgo Biloba also helps fight anxiety and stress.
  • Creativity: the brain booster will also make you more creative and come up with outside-the-box ideas.

Its makers compare it to other leading brain booster substances such as Adderall, Optimind and Profiderall, in terms of availability online without a prescription, ability to increase energy, focus, memory recall, brain power, whether the product is recommended by the doctor and whether there is a 100 percent money back guarantee. The comparison table stresses Synapsyl’s higher ability to improve memory recall and boost brain power and that it is the only product that comes with a 100 percent money back guarantee.

Testimonials listed on the website show the benefits different users experienced, from moms to busy professionals, like increased focus, better memory and mood. Synapsyl helped them stay on top of their busy lives. If the product comparison or the testimonials didn’t convince you, maybe its popularity: the website also lists the number of capsules sold that month.


One of the versions of the website praises phosphatidylcholine, phosphatidylserine, Omega-3 and Bacopin for their amazing results and mentions a couple of studies but with no direct links, but the label lists other ingredients as well. Here’s the full list:

  • One of the main ingredients in Synapsyl, phosphatidylserine, was found to help improve results on memory and intelligence tests according to Pharmacological Research magazine. Total Health Magazine also backs this ingredient for its ability to improve general cognitive performance. Phosphatidylserine is used in the treatment of Alzheimer’s disease, age-related cognitive decline, improving thinking skills in young people, attention deficit-hyperactivity disorder (ADHD), depression, preventing exercise-induced stress, and improving athletic performance.
  • According to a study by the American Journal of Clinical Nutrition, phosphatidylcholine found in Synapsyl can help the brain to metabolize acetylcholine, known as the learning neurotransmitter that helps us remember new information.
  • Another star ingredient is Omega-3, which has been found to have neuroprotective properties, fight anxiety and encourage positive thoughts. Studies have indicated that Omega-3s may be helpful for treating ADHD and Alzheimer’s.
  • Bacopin (20 percent bacosides): the herb Bacopa Monnieri has long been used in traditional Indian medicine for improved learning, memory and information processing. Bacopa has protective antioxidant properties, it boosts blood flow and regulates serotonin release. Studies conducted by the Center for Human Psychopharmacology suggested that Bacopa improves memory and that it enhances cognitive performance.
  • Gingko Biloba (24 percent extract): one of the most popular medicinal plants in the world that’s been around for more than 5,000 years, Ginkgo helps prevent memory loss, including in Alzheimer’s patients, and is recommended for vertigo, headaches, hearing and concentration problems, mood swings and ringing in the ears. It helps prevent brain damage resulting from improper detoxification of the brain by boosting blood circulation.
  • Acetyl-L-Carnitine (ALCAR): helps alleviate the effects of aging like chronic fatigue and cognitive decline, it increase alertness and mitochondrial capacity, repairs neuronal damage and protects the neurons. It is a natural amino acid involved in energy production.
  • John’s Wort (.3% extract): is a herb thought to be effective in treating depression thanks to its ingredients hypericin and hyperforin. However, several studies, including one carried out by the National Center for Complementary and Alternative Medicine (NCCAM), showed that its use had no better effect than in placebo participants.
  • Glutamine (as L-glutamine hydrochloride): is an essential brain neurotransmitter that boosts memory, focus and concentration. Glutamine is an amino acid that is found naturally in the body. When the body has a glutamine deficiency, this results in poor concentration and lack of energy.
  • DMAE Bitartrate: increases acetylcholine levels, protects neurons from oxidation, reduces build-ups of the age pigmentation known as beta-amyloid that impairs cognitive function and leads to cognitive decline with age.
  • Vinpocetine: is thought to improve memory and blood flow.
  • Other ingredients: silica, magnesium stearate and gelatin: magnesium stearate is a cost-effective and harmless additive found in many supplements that act as a lubricant.

Allergic users are warned that the product is manufactured and packaged in a facility which might also process wheat, milk, soy, egg, peanuts, fish and shellfish so it might contain traces of these substances. Vegan users might also be concerned that the supplement contains gelatin which very often comes from animals.

The product claims that scientists call it ‘viagra for the brain’, but the supplement hasn’t been tested scientifically. Otherwise, the study would’ve been described in great detail, instead of mentioning studies about its ingredients.

The FDA does not actually regulate supplements and only intervenes when there have been too many complaints.

Dosage and Side Effects

The recommended dose is two capsules per day.

The website doesn’t only show the label with the full ingredients, but also discloses the supplement’s potential side effects. Not all users react the same way or have the same medical history, so you might not experience either of these. Some of the side effects include photosensitivity leading to skin irritation and redness in people exposed to intense sunlight or tanning booths caused by John’s Wort; bleeding; seizure due to Gingko ingestion; theoretical reduction of fertility; bowel movements, stomach cramps, and nausea caused by bacopa; excessive sweating, stomach upset caused by phosphatidylcholine; or insomnia because of phosphatidylserine.

Patients at risk of bleeding or on anticoagulant medication and couples who are trying to conceive should avoid taking this supplement. Usage should also be stopped a couple of weeks before undergoing surgery. Pregnant women, nursing mothers and underage people should consult a health practitioner beforehand.

Availability and Pricing

The product is made in the USA and is available online through what seems is an official website with two different versions, as well as through a network of independent affiliates. The company behind what appears to be the official website is Anthea Limited and it sells other health supplements, each with its own website, which is rather suspicious since it doesn’t allow the company build credibility across its product line or cross-sell. Another odd feature of one of the versions of the website is that you do not learn what the price is unless you fill in your details: there’s no price on the main page. Then you discover that there are two versions of the site: one that doesn’t list the price, and a more comprehensive one with an entirely different feel that does. There is also this sense of urgency that the stocks are limited, so when you decide to order you click on one of the many Rush my order buttons on the main page.

Synapsyl is available in capsule form. Unlike other supplements, there’s no free trial, unless you consider the 30-day money back guarantee as a free trial period. There are three purchasing options: 1 Bottle for $49.95 plus $9.96 shipping and handling, 3 Bottles at $119.91 plus free shipping, or 5 Bottles for $149.85 plus free shipping.

Synapsyl comes with a 30-day money back guarantee. The product can be returned if the user is not satisfied with Synapsyl for any reason to get a full refund of their money. It is important to note that the 30-day money back guarantee is calculated from the moment the order was placed, not when it was delivered. The trial period is thus reduced. Also, another thing to keep in mind is that the shipping and handling are not covered in the money back guarantee.

To return the product and qualify for a refund, you have to call the Customer Service number to obtain a Return Merchandise Authorization number to be placed on the returned package. Your refund will be processed within 2-5 business days after receipt of the package. The customer service is available 24/7 and there is a contact email [email protected] and three phone lines: one for the USA, one for the UK and one for South Africa.


The product is made of all natural ingredients which are backed up by scientific evidence and have long been known for their benefits. The product comes with a 30-day money back guarantee. There are no free trials linked to auto ship programs that will end up charging your credit card automatically after a month and lead to a lot of back and forth with their customer support team – well at least not on the official website of the product.

Cons and Complaints

The manufacturer makes false claims that scientists call this product ‘viagra for the brain’ but the product hasn’t been tested scientifically and there is no clinical evidence of its benefits, other than the separate benefits of its ingredients, where the dosage of each ingredient might have been different in the respective studies. Some users said they saw no change or results, so an explanation could be that the dosage of each ingredient isn’t right to yield the same results as in the studies.

Individual marketing pitches also suggested it increased IQ by a certain percentage, which is another false claim. Most health supplements will not make you any smarter or more creative, but they will help you think faster, have more clarity of thought and more energy to perform your daily activities and maybe make you a bit happier.

This supplement could have various side effects depending on the consumer’s medical history and sensitivity, including reduced fertility, increased photosensitivity, bleeding, upset stomach, and nausea.

While it’s hard to find genuine customer reviews for supplements, especially when they’re marketed through a network of affiliates, there were a few recurrent customer complaints around efficacy, high price, poor customer support, difficulty cancelling free trials and even auto-ship programs, although the so-called official website doesn’t contain any sign of auto ship programs. There doesn’t seem to be any free trial or auto ship program on the official website, unless the manufacturer changed their marketing strategy. However, since the product is also sold through a network of dealers, their terms and conditions might differ, so make sure you read them carefully before placing an order. Complaints around efficacy are inevitable since our bodies work differently. Also, with customer reviews, it’s quite common for negative reviews to surface since consumers are more likely to take the time to write reviews to complain than to praise.